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COC and COP: medical-grade resins

Cyclic olefin copolymer and cyclo-olefin polymer: clear, low-moisture-uptake resins used for prefillable syringes, vials, diagnostic cartridges and microfluidics.

9 grades from 2 manufacturers. Families included: COC, COP.

Data comes from public supplier literature (cited on each grade page). A blank cell means not stated in the source, not "no". Always confirm with the supplier's current documentation before use.
Reference only: Compiled from public manufacturer literature for reference only; it may be incomplete or outdated. Before using any grade in a device, verify the current manufacturer data sheet and complete your own testing and regulatory review.

All 9 grades

GradeMakerFamilyUSP VIISO 10993GammaEtOAutoclaveVHPFDA file
TOPAS 5013S-04TOPAS Advanced PolymersCOC✔✔no
TOPAS 6013M-07TOPAS Advanced PolymersCOC✔✔
TOPAS 6015S-04TOPAS Advanced PolymersCOC✔✔✔
TOPAS 6017S-04TOPAS Advanced PolymersCOC
TOPAS 8007S-04TOPAS Advanced PolymersCOC✔✔✔✔
ZEONEX 5000ZeonCOP✔✔✔✔no✔DMF
ZEONEX 690RZeonCOP✔✔✔✔✔✔DMF
ZEONEX 790RZeonCOP✔✔✔✔✔✔DMF
ZEONOR 1020RZeonCOP✔✔✔✔no✔DMF

Grades by sterilization statement

The same grades, sorted by what the cited source says for each method. Not stated means the source is silent, not that the grade fails.

Gamma

Stated yes (7): TOPAS 5013S-04 · TOPAS 6015S-04 · TOPAS 8007S-04 · ZEONEX 5000 · ZEONEX 690R · ZEONEX 790R · ZEONOR 1020R

Not stated (2): TOPAS 6013M-07 · TOPAS 6017S-04

EtO

Stated yes (7): TOPAS 5013S-04 · TOPAS 6015S-04 · TOPAS 8007S-04 · ZEONEX 5000 · ZEONEX 690R · ZEONEX 790R · ZEONOR 1020R

Not stated (2): TOPAS 6013M-07 · TOPAS 6017S-04

Steam / autoclave

Stated yes (3): TOPAS 6015S-04 · ZEONEX 690R · ZEONEX 790R

Stated no (3): TOPAS 5013S-04 · ZEONEX 5000 · ZEONOR 1020R

Not stated (3): TOPAS 6013M-07 · TOPAS 6017S-04 · TOPAS 8007S-04

VHP

Stated yes (4): ZEONEX 5000 · ZEONEX 690R · ZEONEX 790R · ZEONOR 1020R

Not stated (5): TOPAS 5013S-04 · TOPAS 6013M-07 · TOPAS 6015S-04 · TOPAS 6017S-04 · TOPAS 8007S-04

Grade data last checked 2026-10-16. Membership uses the same polymer grouping as the tables in MedResin's guides. About the data · Suggest a correction

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