Home › Guides › Which medical plastics survive gamma sterilization?
Which medical plastics survive gamma sterilization?
Gamma irradiation is the default for many single-use devices because it penetrates sealed packaging and leaves no residue. The trade-off is chemical: radiation breaks polymer chains (scission) and forms crosslinks, and it can keep oxidizing the material for weeks or months after exposure. Which effect dominates depends on the polymer.
Of the 338 public grades in MedResin, 209 have gamma compatibility stated by their supplier, 43 are listed as limited, 13 as not suitable, and 73 have no gamma statement in the source.
How polymer families generally behave
- Generally hold up well: polymers with aromatic backbones, such as PEEK, PEI, the sulfones (PSU, PESU, PPSU), PPS, LCP and polystyrene-based resins. Aromatic rings absorb and dissipate radiation energy.
- Usually fine, with caveats: polycarbonate (yellows; suppliers offer radiation-stabilized or color-corrected grades), polyethylene (crosslinking dominates), PET and copolyesters, COC/COP, polyamides, PEBA, silicone, and PVC formulated for irradiation (discoloration is the usual issue). Aromatic TPUs can discolor; aliphatic TPUs are less prone to yellowing.
- Known to be poor: acetal (POM) degrades by chain scission and embrittles; PTFE degrades severely (no PTFE grades are listed in MedResin). Unstabilized polypropylene embrittles, often after a delay, so medical PP for gamma needs a radiation-stabilized grade.
- Check aged parts, not just fresh ones. Post-irradiation oxidation means properties can keep changing after sterilization. Test at the maximum dose your process allows, after real-time or accelerated aging. Dose setting and validation follow ISO 11137.
What MedResin's data shows by polymer group
Counts of supplier gamma statements across all 338 public grades.
Group names and counts link to the matching grade lists.
209 grades with gamma compatibility stated
The dose column is copied as the supplier states it. Blank means the source gives no dose.
| Grade | Maker | Family | Gamma dose (as stated) |
|---|---|---|---|
| OPTIX CA-1000IG | Plaskolite | Acrylic | |
| Carbothane (aliphatic series) | Lubrizol | TPU (aliphatic polycarbonate) | 25 and 50 kGy recommended (single cycle tested) |
| Carbothane PC-3555D | Lubrizol | TPU (aliphatic polycarbonate) | 25 and 50 kGy recommended (single cycle tested) |
| Carbothane PC-3572D | Lubrizol | TPU (aliphatic polycarbonate) | 25 and 50 kGy recommended (single cycle tested) |
| Carbothane PC-3575A | Lubrizol | TPU (aliphatic polycarbonate) | 25 and 50 kGy recommended (single cycle tested) |
| Carbothane PC-3585A | Lubrizol | TPU (aliphatic polycarbonate) | 25 and 50 kGy recommended (single cycle tested) |
| Carbothane PC-3595A | Lubrizol | TPU (aliphatic polycarbonate) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex (aliphatic series) | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex EG-100A | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex EG-60D | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex EG-65D | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex EG-68D | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex EG-72D | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex EG-80A | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex EG-85A | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex EG-93A | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex MG-8020 | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex MG-8812 | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex SG-60D | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex SG-80A | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecoflex SG-85A | Lubrizol | TPU (aliphatic polyether) | 25 and 50 kGy recommended (single cycle tested) |
| Tecophilic HP-60D-20 | Lubrizol | TPU (hydrophilic aliphatic) | 25 and 50 kGy recommended (single cycle tested) |
| Tecophilic HP-60D-35 | Lubrizol | TPU (hydrophilic aliphatic) | 25 and 50 kGy recommended (single cycle tested) |
| Tecophilic HP-60D-60 | Lubrizol | TPU (hydrophilic aliphatic) | 25 and 50 kGy recommended (single cycle tested) |
| Tecophilic HP-93A-100 | Lubrizol | TPU (hydrophilic aliphatic) | 25 and 50 kGy recommended (single cycle tested) |
| Tecophilic SP-60D-60 | Lubrizol | TPU (hydrophilic aliphatic) | 25 and 50 kGy recommended (single cycle tested) |
| Tecophilic SP-80A-150 | Lubrizol | TPU (hydrophilic aliphatic) | 25 and 50 kGy recommended (single cycle tested) |
| Tecophilic SP-93A-100 | Lubrizol | TPU (hydrophilic aliphatic) | 25 and 50 kGy recommended (single cycle tested) |
| TOPAS 5013S-04 | TOPAS Advanced Polymers | COC | |
| TOPAS 6015S-04 | TOPAS Advanced Polymers | COC | |
| TOPAS 8007S-04 | TOPAS Advanced Polymers | COC | |
| ZEONEX 5000 | Zeon | COP | |
| ZEONEX 690R | Zeon | COP | |
| ZEONEX 790R | Zeon | COP | |
| ZEONOR 1020R | Zeon | COP | |
| Vectra MT 1300 | Celanese | LCP | |
| Vectra MT 1310 | Celanese | LCP (30% GF) | |
| Vectra MT 4310 | Celanese | LCP (30% GF) | |
| Vectra MT 4350 | Celanese | LCP (40% mineral) | |
| Vectra MT 1335 | Celanese | LCP (glass/PTFE) | |
| Pebax 1074 SA 01 MED | Arkema | PEBA | |
| Pebax 2533 SA 01 MED | Arkema | PEBA | |
| Pebax 3533 SA 01 MED | Arkema | PEBA | |
| Pebax 4033 SA 01 MED | Arkema | PEBA | |
| Pebax 4533 SA 01 MED | Arkema | PEBA | |
| Pebax 5533 SA 01 MED | Arkema | PEBA | |
| Pebax 6333 SA 01 MED | Arkema | PEBA | |
| Pebax 7033 SA 01 MED | Arkema | PEBA | |
| Pebax 7233 SA 01 MED | Arkema | PEBA | |
| VESTAMID Care ME26 | Evonik | PEBA | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ME40 | Evonik | PEBA | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ME47 | Evonik | PEBA | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ME55 | Evonik | PEBA | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ME62 | Evonik | PEBA | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ME71 | Evonik | PEBA | up to 50 kGy (all Evonik Care grades) |
| VESTAKEEP Care M20 G | Evonik | PEEK | up to 50 kGy (all Evonik Care grades) |
| VESTAKEEP Care M33 G-HP | Evonik | PEEK | up to 50 kGy (all Evonik Care grades) |
| VESTAKEEP Care M40 G | Evonik | PEEK | up to 50 kGy (all Evonik Care grades) |
| PEEK-OPTIMA (family) | Invibio (Victrex) | PEEK | |
| Zeniva ZA-600 | Syensqo (Solvay) | PEEK | |
| TECAPEEK MT natural | Ensinger | PEEK (stock shapes) | |
| ULTEM HU1000 | SABIC | PEI | |
| ULTEM HU1010 | SABIC | PEI | |
| ULTEM HU1100 | SABIC | PEI | |
| ULTEM HU2100 | SABIC | PEI (10% GF) | |
| ULTEM HU2200 | SABIC | PEI (20% GF) | |
| ULTEM HU2300 | SABIC | PEI (30% GF) | |
| ULTEM HU1004 | SABIC | PEI blend | |
| Fortron MT 9140L4 | Celanese | PPS (40% GF) | |
| Fortron MT 9140L6 | Celanese | PPS (40% GF) | |
| APEX 32043RV-NT1 | Teknor Apex | PVC | |
| APEX 33043RV-NT1 | Teknor Apex | PVC | |
| Kynar 720 MED | Arkema | PVDF | |
| TROGAMID Care MX73 | Evonik | PA (transparent microcrystalline) | up to 50 kGy (all Evonik Care grades) |
| TROGAMID Care MX97 | Evonik | PA (transparent microcrystalline) | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ML16 | Evonik | PA12 | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ML17 | Evonik | PA12 | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ML18 | Evonik | PA12 | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ML19 | Evonik | PA12 | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ML21 | Evonik | PA12 | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ML24 | Evonik | PA12 | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ML67 | Evonik | PA12 | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care ML94 | Evonik | PA12 | up to 50 kGy (all Evonik Care grades) |
| VESTAMID Care MLGB30 | Evonik | PA12 (glass beads) | up to 50 kGy (all Evonik Care grades) |
| Makrolon 2258 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon 2458 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon 2558 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon 2658 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon 2858 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon 3158 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon 3258 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon 3638 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon Rx1452 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon Rx1805 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon Rx1851 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon Rx2235 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon Rx2430 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon Rx2435 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon Rx2440 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon Rx2530 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon Rx2635 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon Rx3440 | Covestro | PC | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Apec 1745 | Covestro | PC (high-heat) | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Apec 2045 | Covestro | PC (high-heat) | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon M204 LF | Covestro | PC (low friction) | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon M402 LF | Covestro | PC (low friction) | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon M404 LF | Covestro | PC (low friction) | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Bayblend M750 | Covestro | PC/ABS | |
| Bayblend M850 XF | Covestro | PC/ABS | |
| Makrolon M410 GF | Covestro | PC/GF | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon M420 GF | Covestro | PC/GF | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon M430 GF | Covestro | PC/GF | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon M810 GF | Covestro | PC/GF | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon M820 GF | Covestro | PC/GF | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makrolon M830 GF | Covestro | PC/GF | 28 kGy assumed per sterilization; 10-20 sterilizations before appreciable strength loss (Makrolon/Apec, per Covestro) |
| Makroblend M525 | Covestro | PC/PBT | |
| Eastar MN005 | Eastman | Copolyester | |
| Eastar MN006 | Eastman | Copolyester | |
| Tritan MX710 | Eastman | Copolyester | |
| Tritan MX711 | Eastman | Copolyester | tested at 50 kGy (minimal color shift; Eastman) |
| Tritan MX731 | Eastman | Copolyester | |
| Tritan MX811 | Eastman | Copolyester | |
| Ultradur PRO B4521 | BASF | PBT | |
| Celanex 2401MT | Celanese | PBT | |
| Celanex 2402MT | Celanese | PBT | |
| Celanex 2405MT | Celanese | PBT | |
| Eastar MN052 | Eastman | Polyester | |
| GUR 1001 | Celanese | UHMW-PE | |
| GUR 1020 | Celanese | UHMW-PE | |
| GUR 1020-E | Celanese | UHMW-PE | |
| GUR 1050 | Celanese | UHMW-PE | |
| GUR 1050-E | Celanese | UHMW-PE | |
| Bormed HD810MO | Borealis | PP | |
| Bormed RF830MO | Borealis | PP | |
| 11R12A | INVISTA | PP | |
| 12G50M | INVISTA | PP | |
| 13R9A | INVISTA | PP | |
| 23R2A | INVISTA | PP | |
| 23R2B | INVISTA | PP | |
| P5M6K-080 | INVISTA | PP | |
| P9M7R-056 | INVISTA | PP | |
| Purell PF511 | LyondellBasell | PP | |
| Purell PF531 | LyondellBasell | PP | |
| 3740WR | TotalEnergies | PP | good gamma radiation stability up to 50 kGy |
| 3847MR | TotalEnergies | PP | |
| 3944MR | TotalEnergies | PP | |
| Silopren LSR 4060 | Momentive | LSR | |
| Silopren LSR 4080 | Momentive | LSR | |
| Silopren LSR 4660 | Momentive | LSR | |
| Lustran 348 | INEOS Styrolution | ABS | |
| Novodur HD 15 | INEOS Styrolution | ABS | |
| Novodur HD M203FC | INEOS Styrolution | ABS | |
| Luran S MED 797S FC | INEOS Styrolution | ASA | |
| Luran S MED 797S SPF30 | INEOS Styrolution | ASA | |
| Terlux HD 2802/2822 | INEOS Styrolution | MABS | |
| Terlux HD 2812 | INEOS Styrolution | MABS | |
| Clearblend 145 | INEOS Styrolution | MBS | |
| Clearblend 165 | INEOS Styrolution | MBS | |
| Zylar 245 | INEOS Styrolution | MBS | |
| Zylar 550 | INEOS Styrolution | MBS | |
| Zylar 631 | INEOS Styrolution | MBS | |
| Zylar 650 | INEOS Styrolution | MBS | |
| Zylar 960 | INEOS Styrolution | MBS | |
| Styroflex 2G66 | INEOS Styrolution | S-TPE | |
| Styroflex 4G80 | INEOS Styrolution | S-TPE | |
| Luran HD 20 TR64000 | INEOS Styrolution | SAN | |
| K-Resin KR01 | INEOS Styrolution | SBC | |
| K-Resin KR03/KR05/DK11 | INEOS Styrolution | SBC | |
| Styrolux 3G46 | INEOS Styrolution | SBC | |
| Styrolux 656C | INEOS Styrolution | SBC | |
| Styrolux 684D | INEOS Styrolution | SBC | |
| NAS 21 | INEOS Styrolution | SMMA | |
| NAS 30 | INEOS Styrolution | SMMA | |
| NAS 90 | INEOS Styrolution | SMMA | |
| Ultrason E 2010 | BASF | PESU | noticeable property decline only above 2 MGy (Ultrason E) |
| Ultrason E 3010 | BASF | PESU | noticeable property decline only above 2 MGy (Ultrason E) |
| Radel R-5000 | Syensqo (Solvay) | PPSU | |
| Radel R-5100 | Syensqo (Solvay) | PPSU | |
| Ultrason S 2010 | BASF | PSU | |
| Udel P-1700 | Syensqo (Solvay) | PSU | |
| Medalist MD-91760 | Teknor Apex | TPE (biopharma tubing) | |
| Medalist MD-91970 | Teknor Apex | TPE (biopharma tubing) | |
| Medalist MD-92260 | Teknor Apex | TPE (biopharma tubing) | |
| Medalist MD-96267 | Teknor Apex | TPE (biopharma tubing) | |
| Medalist MD-12337 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-12342 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-12352 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-12362 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-12368 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-12372 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-12382 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-36165 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-53253 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-53263 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-53268 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-53273 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-53278 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-53283 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-53288 | Teknor Apex | TPE (medical tubing) | |
| Medalist MD-53293 | Teknor Apex | TPE (medical tubing) | |
| Texin RxS285 | Covestro | TPU | |
| Texin RxS292 | Covestro | TPU | |
| Texin RxT50D | Covestro | TPU | |
| Texin RxT65D | Covestro | TPU | |
| Texin RxT70A | Covestro | TPU | |
| Texin RxT76D | Covestro | TPU | |
| Texin RxT80A | Covestro | TPU | |
| Texin RxT85A | Covestro | TPU | |
| Texin RxT90A | Covestro | TPU |
56 grades listed as limited or not suitable for gamma
"Limited" covers cases such as discoloration or a restricted dose or cycle count; see each grade page for the supplier's wording.
See also: all gamma-compatible grades · gamma-stable polypropylene · sterilization methods guide
Grade data last checked 2026-10-16. Blank cells mean not stated by the source. Each grade page cites its source. About the data · Suggest a correction
More guides: Autoclave-safe resins compared · USP Class VI vs ISO 10993 · EtO-compatible materials for catheters and tubing · Choosing a TPU for medical tubing · All guides
Overview of every polymer group: Medical-grade plastics: grades by polymer and sterilization